Some of the biggest opportunities are to take many of the very rapidly converging and accelerating technologies and blend them together in powerful ways to change everything from how we do health and wellness, to diagnosis, therapy and even how we might think about discovery.

Consumers are becoming the CEO of their own health, and it's no longer the paternalistic pattern of "go to the physician, he may tell you what to do." You can now access more information; you can gain insights about your own conditions, whether that's your baseline genetics or your blood pressure or your management of more complex diseases like diabetes. And I think that empowers both the individual and the caregiver to have a more integrated experience.

The second trend would be that of personalization. There's a lot of buzz around personalized medicine or the Precision Medicine Initiative; technology is going to enable that in more impactful ways. An obvious example would be consumer or personalized genomics. The price of sequencing a whole genome has dropped at twice the rate of Moore's Law. It was millions of dollars and took weeks to months, a decade ago, and now it's down to about $1,000, and soon will be less than the price of a standard x-ray.

A third trend that layers on top of the first two would be the "Internet of Things" blending with the "Internet of Health". We're now well into the era of quantified-self type technologies. I think we'll move to an era where, just like our modern cars have a check engine light based on hundreds of sensors, we'll see some of that come to our health and medicine. We will be able to take signals from our social networks and from our wearable devices; things embedded in our clothes, in the refrigerator, in the mattress, and use those to give us useful, actionable information. I like to call that "predictalytics".

Another meta trend I mentioned would be that most of crowdsourcing. We can now donate our genetic information, like with 23andMe–the sister of the 23andWe platform. I think we'll see more and more folks interested in becoming data donors, volunteering elements of their data or healthcare information, and, in exchange, getting something back. Hopefully, we'll see that sort of crowdsourcing and participatory medicine spread between academic groups and electronic medical records. Whereas today, a lot of that information is siloed and not very accessible, that's going to shift.

The Apple Watch, for example, has a fair number of health sensors in it. But what was more interesting for me during that announcement was the Apple ResearchKit, which is a layer on top of Healthkit but it's going to transform how we do clinical trials. You can now download from the Apple Store, six or more different clinical trials. It enables, again, the citizen to become a participatory contributor to healthcare innovation. And I would imagine pharmaceutical companies and others in the future, pushing or making available trials to folks who are candidates, and they will benefit potentially from being in the trial, and speeding up the path to, whether it's a new drug or a new app, or a new platform across different elements of health and medicine.

3D printing is another impactful trend. We're already in the era where most hearing aids and technologies like braces are 3D printed. We're going to see 3D printing emerge into orthopedics. There are already earlier versions of implantable hips and knees that can be based on the patient's anatomy. It may even be your own 3D printed cardiac stent to match your anatomy, all of which is really possible today, but it's going to become much more applicable across different elements of health and medicine.

I think as we see these tools become more integrated seamlessly into the physician workflow, using technologies ranging from Google Glass and other forms of augmented reality, to using artificial intelligence to help make sense of the means of new data that are available, we'll start to see that physicians and other healthcare providers find that these have a value, and improve the quality and efficiency of their care, improve outcomes, it can even improve the patient-doctor relationships.

When incentives are aligned, meaning a physician who's no longer paid fee-for-service, their pay is getting bonus by having better outcomes, we'll see these become utilized. And again, that's often about understanding the culture and misaligned incentives.